The e-Science 2005 conference, sponsored by the IEEE Computer Society Technical Committee for Scalable Computing (TCSC) and Society for Industrial and Applied Mathematics (SIAM), is designed to bring together leading international and interdisciplinary research communities, developers, and users of e-Science applications and enabling IT technologies. The conference serves as a forum to present the results of the latest research and product/tool developments, and highlight related activities from around the world. For further information, please see: its Website.